The Effects Of Dietary Fiber Feeding On Cholesterol Metabolism In Rats

Plasma cholesterol levels hepatic enzyme activity and fecal bile acid excretion were determined and changes in the intestinal structure were evaluated.

The effects of dietary fiber feeding on cholesterol metabolism in rats. The present study was designed to examine the effects of the dietary fiber supplementation on serum levels of glucose and lipoproteins in cholesterol fed diabetic rats. The effects of mushroom fibers on serum cholesterol and hepatic low density lipoprotein ldl receptor mrna in rats were investigated. Rats were fed a cholesterol free diet with 50 g kg cellulose powder cp 50 g kg maitake grifola frondosa fiber maf 50 g kg shiitake lentinus edodes fiber sf or 50 g kg enokitake flammulina velutipes fiber ef for 4 weeks.

The present study was aimed to investigate the effects of indigestible dextrin and polydextrose soluble dietary fibers with low molecular weight on lipid metabolism and disaccharidase activities of intestinal mucosa in rats fed a high sucrose diet. Nishina pm 1 freedland ra. Cholesterol absorption is altered by various dietary fiber sources but not consistently by all.

This study was designed to investigate the effects of pectin on cholesterol and bile acid metabolism and to elucidate the mechanisms involved in its hypolipidemic effect in rats. The key regulatory enzymes in cholesterol and bile acid metabolism 3 hydroxy 3 methylglutaryl coa reductase hmg coa red. Balmer and zilversmit 1974 reported little difference the role of dietary fiber 237 in cholesterol absorption in rats as measured by the plasma isotope ratio m e t h o d from a stock diet as compared to a semipurified diet.

This study was undertaken to determine whether selected dietary fibers had an effect on plasma lipoproteins apolipoproteins and enzymes involved in cholesterol metabolism in rats. Feeding a diet containing 1 5 cholesterol wt wt and 0 37 cholic acid for 18 weeks to rats made diabetic by streptozotocin 35 mg kg body weight iv produced moderate. Effects of 0 03 polychlorinated biphenyls pcb in the diet and various dietary fibers konjac mannan km pectin sodium carboxymethyl cellulose cmc and cellulose at a 5 level in the diet on serum and liver.

High fiber diet feeding reduced apo a i mrna levels in jejunum and ileum and ileal apo a iv mrna levels as compared to fiber free diet fed rats. The flux through the sterol biosynthetic pathway was studied in hepatocytes isolated from male sprague dawley rats fed diets containing one of four fiber sources. 1 school of veterinary medicine university of california davis 95616.

The obtained results suggest that some dietary fibers may play a role in regulation of lipoprotein metabolism in the intestine including apolipoprotein synthesis. Thirty male sprague dawley rats were divided into 3 groups and fed either a fiber free 15 fiber high methoxy pectin or 15 cellulose diet for a 4 wk period.