Dietary Fiber Intake And Risk Of Colorectal Cancer

When the association between fiber intake and risk of colorectal cancer was analyzed with fiber as a continuous variable the results were largely similar with a borderline association for total fiber hr per 5 g 1000 kcal increment.

Dietary fiber intake and risk of colorectal cancer. Dietary fiber intake was estimated from food frequency questionnaires comprising 44 or 52 items at the baseline survey and 138 food items at a 5 year follow up. The association of dietary fiber intake with colorectal cancer risk has been inconclusive among epidemiologic studies. Dietary fiber has been associated with a reduced risk of colorectal cancer.

Here we investigate the association of fruit vegetables and fiber intake with four well established. The association between dietary fiber intake and risk of colorectal cancer was not significantly modified by sex or age at diagnosis. Compared with the lowest quintile the pooled multivariate rr for the highest quintile was 0 96 95 ci 0 82 1 13 for men.

An updated analysis according to food sources tumor location and molecular subtypes in two large us cohorts int j cancer. Consequently the authors investigated the association between dietary fiber intake and the subsequent risk of colorectal cancer in a prospective cohort study of a japanese population. 1 a meta analysis of 13 case control studies provided verifiable evidence of an inverse association between fiber rich foods.

1000 kcal 1. Dietary intake of fiber whole grains and risk of colorectal cancer. 0 93 95 ci 0 83 1 04 for women.

P for between studies heterogeneity due to sex. Protective associations of fruits vegetables and fiber intake with colorectal cancer risk have been shown in many but not all epidemiologic studies. However it remains unclear at which stage in the carcinogenic pathway fiber may act or which food sources of dietary fiber may be most beneficial against colorectal cancer development.

Many case control studies showed results corresponding to laboratory findings demonstrating an anticarcinogenic effect in the colon or rectum. 2 p trend 0 05 all statistical tests were 2 sided.